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butabarbital, calcium/magnesium/potassium/sodium oxybates. Either raises outcomes of one other by pharmacodynamic synergism. Contraindicated. Coadministration with Liquor or sedative hypnotics are contraindicated due to additive CNS despair.butabarbital will lessen the level or effect of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 me